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Leu AJ, Berk DA, Yuan F, Jain RK

Flow velocity in the superficial lymphatic network of the mouse tail.
Am J Physiol. 1994;267(4 Pt 2):H1507-13 - PMID: 7943396 - DOI: 10.1152/ajpheart.1994.267.4.H1507

Melder RJ, Elmaleh D, Brownell AL, Brownell GL, Jain RK

A method for labeling cells for positron emission tomography (PET) studies.
J Immunol Methods. 1994;175(1):79-87 - PMID: 7930641 - DOI: 10.1016/0022-1759(94)90333-6

Melder RJ, Jain RK

Reduction of rigidity in human activated natural killer cells by thioglycollate treatment.
J Immunol Methods. 1994;175(1):69-77 - PMID: 7930640 - DOI: 10.1016/0022-1759(94)90332-8

Martin GR, Jain RK

Noninvasive measurement of interstitial pH profiles in normal and neoplastic tissue using fluorescence ratio imaging microscopy.
Cancer Res. 1994;54(21):5670-4 - PMID: 7923215

Kristjansen PE, Roberge S, Lee I, Jain RK

Tissue-isolated human tumor xenografts in athymic nude mice.
Microvasc Res. 1994;48(3):389-402 - PMID: 7731400 - DOI: 10.1006/mvre.1994.1063

Xie K, Bielenberg D, Huang S, Xu L, Salas T, Juang SH, Dong Z, Fidler IJ

Abrogation of tumorigenicity and metastasis of murine and human tumor cells by transfection with the murine IFN-beta gene: possible role of nitric oxide.
Clin Cancer Res. 1997;3(12 Pt 1):2283-94 - PMID: 9815626

Xu L, Czito BG, Willett CG

Epigenetic markers in rectal cancer.
Clin Cancer Res. 2010;16(10):2699-701 - PMID: 20460492 - DOI: 10.1158/1078-0432.CCR-10-0559

Fidler IJ, Yoneda J, Herrera C, Wood J, Xu L

Specific Keynote: Molecular determinants of angiogenesis in ovarian cancer
Gynecologic Oncology. 2003;88:S290S36

Fidler IJ, Bielenberg DR, Slaton J, Xu L, Dinney CPN, Dong Z

Interferon-mediated antiangiogenic therapy
Journal of National Cancer Institute. 2000;1092:4-12

Fidler IJ, Singh RK, Yoneda J, Kumar R, Xu L, Dong Z, Bielenberg DR, McCarty M, Ellis LM

Critical determinants of neoplastic angiogenesis
The Cancer Journal. 2000;6 Suppl 3:S225-36 - PMID: 10874492

Xu L, Fidler IJ

Interleukin 8: an autocrine growth factor for human ovarian cancer.
Oncol Res. 2000;12(2):97-106 - PMID: 11132928 - DOI: 10.3727/096504001108747567

Xu L, Yoneda J, Herrera C, Wood J, Killion JJ, Fidler IJ

Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases.
Int J Oncol. 2000;16(3):445-54 - PMID: 10675474 - DOI: 10.3892/ijo.16.3.445

Xu L, Fidler IJ

Acidic pH-induced elevation in interleukin 8 expression by human ovarian carcinoma cells.
Cancer Res. 2000;60(16):4610-6 - PMID: 10969814

Xu L, Xie K, Mukaida N, Matsushima K, Fidler IJ

Hypoxia-induced elevation in interleukin-8 expression by human ovarian carcinoma cells.
Cancer Res. 1999;59(22):5822-9 - PMID: 10582705

Xu L, Xie K, Fidler IJ

Therapy of human ovarian cancer by transfection with the murine interferon beta gene: role of macrophage-inducible nitric oxide synthase.
Hum Gene Ther. 1998;9(18):2699-708 - PMID: 9874268 - DOI: 10.1089/hum.1998.9.18-2699

Juang SH, Xie K, Xu L, Shi Q, Wang Y, Yoneda J, Fidler IJ

Suppression of tumorigenicity and metastasis of human renal carcinoma cells by infection with retroviral vectors harboring the murine inducible nitric oxide synthase gene.
Hum Gene Ther. 1998;9(6):845-54 - PMID: 9581907 - DOI: 10.1089/hum.1998.9.6-845

Juang SH, Xie K, Xu L, Wang Y, Yoneda J, Fidler IJ

Use of retroviral vectors encoding murine inducible nitric oxide synthase gene to suppress tumorigenicity and cancer metastasis of murine melanoma.
Cancer Biother Radiopharm. 1997;12(3):167-75 - PMID: 10851463 - DOI: 10.1089/cbr.1997.12.167

Herrera CA, Xu L, Bucana CD, Silva el VG, Hess KR, Gershenson DM, Fidler IJ

Expression of metastasis-related genes in human epithelial ovarian tumors.
Int J Oncol. 2002;20(1):5-13 - PMID: 11743636

Xie K, Wang Y, Huang S, Xu L, Bielenberg D, Salas T, McConkey DJ, Jiang W, Fidler IJ

Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2.
Oncogene. 1997;15(7):771-9 - PMID: 9266963 - DOI: 10.1038/sj.onc.1201239

Schwabl P, Payer BA, Grahovac J, Klein S, Horvatits T, Mitterhauser M, Stift J, Boucher Y, Trebicka J, Trauner M, Angermayr B, Fuhrmann V, Reiberger T, Peck-Radosavljevic M

Pioglitazone decreases portosystemic shunting by modulating inflammation and angiogenesis in cirrhotic and non-cirrhotic portal hypertensive rats.
J Hepatol. 2014;60(6):1135-42 - PMID: 24530596 - DOI: 10.1016/j.jhep.2014.01.025

Jain RK

Delivery of molecular and cellular medicine to solid tumors.
Adv Drug Deliv Rev. 2012;64(Suppl):353-365 - PMID: 24511174 - PMCID: PMC3914635 - DOI: 10.1016/j.addr.2012.09.011

Jain RK

An indirect way to tame cancer
Sci Am. 2014;310(2):46-53 - PMID: 24640331 - DOI: 10.1038/scientificamerican0214-46

Kirkpatrick ND, Chung E, Cook DC, Han X, Gruionu G, Liao S, Munn LL, Padera TP, Fukumura D, Jain RK

Video-rate resonant scanning multiphoton microscopy: An emerging technique for intravital imaging of the tumor microenvironment.
Intravital. 2012;1(1):ePub - PMID: 24353926 - PMCID: PMC3864876 - DOI: 10.4161/intv.21557

Duda DG

Molecular Biomarkers of Response to Antiangiogenic Therapy for Cancer.
ISRN Cell Biol. 2013;2012:ePub - PMID: 24340224 - PMCID: PMC3856765 - DOI: 10.5402/2012/587259

Munn LL

Dynamics of tissue topology during cancer invasion and metastasis.
Phys Biol. 2013;10(6):065003 - PMID: 24304856 - PMCID: PMC4324506 - DOI: 10.1088/1478-3975/10/6/065003

Pinho MC, Polaskova P, Kalpathy-Cramer J, Jennings D, Emblem KE, Jain RK, Rosen BR, Wen PY, Sorensen AG, Batchelor TT, Gerstner ER

Low Incidence of Pseudoprogression by Imaging in Newly Diagnosed Glioblastoma Patients Treated With Cediranib in Combination With Chemoradiation.
Oncologist. 2014;19(1):75-81 - PMID: 24309981 - PMCID: PMC3903059 - DOI: 10.1634/theoncologist.2013-0101

Chan-On W, Nairismägi ML, Ong CK, Lim WK, Dima S, Pairojkul C, Lim KH, McPherson JR, Cutcutache I, Heng HL, Ooi L, Chung A, Chow P, Cheow PC, Lee SY, Choo SP, Tan IB, Duda D, Nastase A, Myint SS, Wong BH, Gan A, Rajasegaran V, Ng CC, Nagarajan S, Jusakul A, Zhang S, Vohra P, Yu W, Huang D, Sithithaworn P, Yongvanit P, Wongkham S, Khuntikeo N, Bhudhisawasdi V, Popescu I, Rozen SG, Tan P, Teh BT

Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers.
Nat Genet. 2013;45(12):1474-8 - PMID: 24185513 - DOI: 10.1038/ng.2806

Chen Y, Huang Y, Reiberger T, Duyverman AM, Huang P, Samuel R, Hiddingh L, Roberge S, Koppel C, Lauwers GY, Zhu AX, Jain RK, Duda DG

Differential effects of sorafenib on liver versus tumor fibrosis mediated by SDF1a/CXCR4 axis and Gr-1+ myeloid cell infiltration in mice.
Hepatology. 2014;59(4):1435-47 - PMID: 24242874 - PMCID: PMC3966948 - DOI: 10.1002/hep.26790

Huang Y, Stylianopoulos T, Duda DG, Fukumura D, Jain RK

Benefits of Vascular Normalization Are Dose and Time Dependent--Letter.
Cancer Res. 2013;73(23):7144-6 - PMID: 24265277 - PMCID: PMC3876035 - DOI: 10.1158/0008-5472.CAN-13-1989

Kaufman EN, Jain RK

In vitro measurement and screening of monoclonal antibody affinity using fluorescence photobleaching.
J Immunol Methods. 1992;155(1):1-17 - PMID: 1383343 - DOI: 10.1016/0022-1759(92)90265-u

Baxter LT, Jain RK

Transport of fluid and macromolecules in tumors. IV. A microscopic model of the perivascular distribution.
Microvasc Res. 1991;41(2):252-72 - PMID: 2051960 - DOI: 10.1016/0026-2862(91)90026-8

Baxter LT, Jain RK

Transport of fluid and macromolecules in tumors. III. Role of binding and metabolism.
Microvasc Res. 1991;41(1):5-23 - PMID: 2051954 - DOI: 10.1016/0026-2862(91)90003-t

Sasaki A, Melder RJ, Whiteside TL, Herberman RB, Jain RK

Preferential localization of human adherent lymphokine-activated killer cells in tumor microcirculation.
J Natl Cancer Inst. 1991;83(6):433-7 - PMID: 1999850 - DOI: 10.1093/jnci/83.6.433

Sevick EM, Jain RK

Measurement of capillary filtration coefficient in a solid tumor.
Cancer Res. 1991;51(4):1352-5 - PMID: 1997172

Jain RK

Therapeutic implications of tumor physiology.
Curr Opin Oncol. 1991;3(6):1105-8 - PMID: 1843113 - DOI: 10.1097/00001622-199112000-00020

Leunig M, Goetz AE, Dellian M, Zetterer G, Gamarra F, Jain RK, Messmer K

Interstitial fluid pressure in solid tumors following hyperthermia: possible correlation with therapeutic response.
Cancer Res. 1992;52(2):487-90 - PMID: 1728421

Jain RK

Haemodynamic and transport barriers to the treatment of solid tumours.
Int J Radiat Biol. 1991;60(1-2):85-100 - PMID: 1678003 - DOI: 10.1080/09553009114551621

Kaufman EN, Jain RK

Effect of bivalent interaction upon apparent antibody affinity: experimental confirmation of theory using fluorescence photobleaching and implications for antibody binding assays.
Cancer Res. 1992;52(15):4157-67 - PMID: 1638531

Gutmann R, Leunig M, Feyh J, Goetz AE, Messmer K, Kastenbauer E, Jain RK

Interstitial hypertension in head and neck tumors in patients: correlation with tumor size.
Cancer Res. 1992;52(7):1993-5 - PMID: 1551128

Eskey CJ, Koretsky AP, Domach MM, Jain RK

2H-nuclear magnetic resonance imaging of tumor blood flow: spatial and temporal heterogeneity in a tissue-isolated mammary adenocarcinoma.
Cancer Res. 1992;52(21):6010-9 - PMID: 1394226

Baxter LT, Yuan F, Jain RK

Pharmacokinetic analysis of the perivascular distribution of bifunctional antibodies and haptens: comparison with experimental data.
Cancer Res. 1992;52(20):5838-44 - PMID: 1394212

Hagendoorn J, Yock TI, Borel Rinkes IH, Padera TP, Ebb DH

Novel molecular pathways in Gorham disease: Implications for treatment.
Pediatr Blood Cancer. 2014;61(3):401-6 - PMID: 24214028 - PMCID: PMC4123459 - DOI: 10.1002/pbc.24832

Melder RJ, Jain RK

Kinetics of interleukin-2 induced changes in rigidity of human natural killer cells.
Cell Biophys. 1994;20(2-3):161-76 - PMID: 1285298 - DOI: 10.1007/BF02823656

Weissbrod JM, Jain RK, Sirotnak FM

Pharmacokinetics of methotrexate in leukemia cells: effect of dose and mode of injection.
J Pharmacokinet Biopharm. 1978;6(6):487-503 - PMID: 731413 - DOI: 10.1007/BF01062105

Lee JJ, Perera RM, Wang H, Wu DC, Liu XS, Han S, Fitamant J, Jones PD, Ghanta KS, Kawano S, Nagle JM, Deshpande V, Boucher Y, Kato T, Chen JK, Willmann JK, Bardeesy N, Beachy PA

Stromal response to Hedgehog signaling restrains pancreatic cancer progression.
Proc Natl Acad Sci U S A. 2014;111(30):E3091-100 - PMID: 25024225 - PMCID: PMC4121834 - DOI: 10.1073/pnas.1411679111

Chauhan VP, Boucher Y, Ferrone CR, Roberge S, Martin JD, Stylianopoulos T, Bardeesy N, DePinho RA, Padera TP, Munn LL, Jain RK

Compression of Pancreatic Tumor Blood Vessels by Hyaluronan Is Caused by Solid Stress and Not Interstitial Fluid Pressure.
Cancer Cell. 2014;26(1):14-15 - PMID: 25026209 - PMCID: PMC4381566 - DOI: 10.1016/j.ccr.2014.06.003

Jain RK, Martin JD, Stylianopoulos T

The role of mechanical forces in tumor growth and therapy.
Annu Rev Biomed Eng. 2014;16:321-46 - PMID: 25014786 - PMCID: PMC4109025 - DOI: 10.1146/annurev-bioeng-071813-105259

Wang Y, Li W, Patel SS, Cong J, Zhang N, Sabbatino F, Liu X, Qi Y, Huang P, Lee H, Taghian A, Li JJ, DeLeo AB, Ferrone S, Epperly MW, Ferrone CR, Ly A, Brachtel EF, Wang X

Blocking the formation of radiation-induced breast cancer stem cells.
Oncotarget. 2014;5(11):3743-55 - PMID: 25003837 - PMCID: PMC4116517 - DOI: 10.18632/oncotarget.1992

Munn LL, Padera TP

Imaging the Lymphatic System.
Microvasc Res. 2014;96C:55-63 - PMID: 24956510 - PMCID: PMC4268344 - DOI: 10.1016/j.mvr.2014.06.006

Hato T, Goyal L, Greten TF, Duda DG, Zhu AX

Immune checkpoint blockade in hepatocellular carcinoma: Current progress and future directions.
Hepatology. 2014;60(5):1776-82 - PMID: 24912948 - PMCID: PMC4211962 - DOI: 10.1002/hep.27246
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