Duda Lab

Tesfay MZ, Cios A, Ferdous KU, Shelton RS, Mustafa B, Simoes CC, Gokden M, Miousse IR, Krager KJ, Boerma M, Urbaniak A, Kunthur A, Obulareddy S, Eichhorn JM, Post SR, Chamcheu JC, Moaven O, Chabu CY, Duda DG, Conti M, Nardo B, Govindarajan R, Fernandez-Zapico ME, Roberts LR, Borad MJ, Cannon MJ, Basnakian AG, Nagalo BM

Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models.
Front Immunol. 2025;16:1679665 - PMID: 41142777 - PMCID: PMC12546120 - DOI: 10.3389/fimmu.2025.1679665

Dima SO, Sorop A, Kitahara S, Setia N, Chivu-Economescu M, Matei L, Herlea V, Pechianu NC, Inomata T, Matsui A, Khachatryan A, Aoki S, Lauwers GY, Popescu I, Duda DG

A tumor microenvironment-based classification of gastric cancer for more effective diagnosis and treatment.
Surg Oncol. 2025;63:102298 - PMID: 41033926 - DOI: 10.1016/j.suronc.2025.102298

Duda DG, Abdel Wahab M, Takaori K

Thirty-Five years of globalizing surgical oncology knowledge: A look into the future - IASGO Cairo 2024.
Surg Oncol. 2025;63:102294 - PMID: 40967991 - DOI: 10.1016/j.suronc.2025.102294

Duda DG, Javle M

A GOLP rush in biliary tract cancer: early promise in the quest for curative surgery.
Lancet Oncol. 2025;26(10):1265-1267 - PMID: 40889501 - DOI: 10.1016/S1470-2045(25)00427-9

Talele NP, Kumra H, Gomes-Santos IL, Ho WW, Andersson P, Siwicki M, Huang P, Duda DG, Pittet MJ, Fukumura D, Jain RK

IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against pancreatic cancer in mice with obesity.
J Immunother Cancer. 2025;13(5):ePub - PMID: 40413022 - PMCID: PMC12104899 - DOI: 10.1136/jitc-2024-011404

Duda D, Liu X, Liu Z, Kobayashi T, Lei PJ, Shi Y, Yuan D, Wang J, Li M, Matsui A, Mafra K, Huang P, Kuang M, Bod L

Inhibiting B-cell-mediated Immunosuppression to Enhance the Immunotherapy Efficacy in Hepatocellular Carcinoma.
Res Sq. 2025;:ePub - PMID: 40321752 - PMCID: PMC12047993 - DOI: 10.21203/rs.3.rs-6355345/v1

Gkika E, Firat E, Adebahr S, Graf E, Popp I, Eichhorst A, Radicioni G, Lo SS, Spohn SKB, Nestle U, Nicolay NH, Niedermann G, Grosu AL, Duda DG

A prospective study of immune responses in patients with lung metastases treated with stereotactic body radiotherapy with or without concurrent systemic treatment.
Radiother Oncol. 2025;207:110889 - PMID: 40209858 - DOI: 10.1016/j.radonc.2025.110889

Saeed A, Colby S, Oberstein PE, Duda DG, Park R, Agarwal R, Figueroa-Moseley C, Vaidya R, Unger JM, Guthrie KA, Rocha FG, Senthil M, Safyan RA, Wainberg ZA, Iqbal S, Chiorean EG, Philip PA

S2303: phase II/III trial of paclitaxel + ramucirumab +/- nivolumab in gastric and esophageal adenocarcinoma (PARAMUNE)
Future Oncol. 2025;21(11):1325-1331 - PMID: 40155326 - PMCID: PMC12051544 - DOI: 10.1080/14796694.2025.2485020

Liu X, Liu Z, Kobayashi T, Lei PJ, Shi Y, Yuan D, Wang J, Li M, Matsui A, Mafra K, Huang P, Kuang M, Bod L, Duda DG

Inhibiting B-cell-mediated Immunosuppression to Enhance the Immunotherapy Efficacy in Hepatocellular Carcinoma.
bioRxiv. 2025;:ePub - PMID: 40093175 - PMCID: PMC11908210 - DOI: 10.1101/2025.03.04.641494

Yan J, Jiang Z, Zhang S, Yu Q, Lu Y, Miao R, Tang Z, Fan J, Wu L, Duda DG, Zhou J, Yang X

Spatial-temporal heterogeneities of liver cancer and the discovery of the invasive zone.
Clin Transl Med. 2025;15(2):e70224 - PMID: 39924620 - PMCID: PMC11807767 - DOI: 10.1002/ctm2.70224

Ren J, Amoozgar Z, Uccello TP, Lei PJ, Zhao Y, Ho WW, Huang P, Kardian A, Mack SC, Duda DG, Xu L, Jain RK

Targeting EPHB2/ABL1 restores antitumor immunity in preclinical models of ependymoma.
Proc Natl Acad Sci U S A. 2025;122(4):e2319474122 - PMID: 39841145 - PMCID: PMC11789170 - DOI: 10.1073/pnas.2319474122
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