Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment.
Nat Genet. 2022;54(8):1178-1191 - PMID: 35902743 - DOI: 10.1038/s41588-022-01134-8
A nonrandomized phase I and biomarker trial of regorafenib in advanced myeloid malignancies.
A Phase I Trial of TB-403 in Relapsed Medulloblastoma, Neuroblastoma, Ewing Sarcoma, and Alveolar Rhabdomyosarcoma.
Clin Cancer Res. 2022;:ePub - PMID: 35833850 - DOI: 10.1158/1078-0432.CCR-22-1169
The local microenvironment matters in preclinical basic and translational studies of cancer immunology and immunotherapy.
Cancer Cell. 2022;40(7):701-702 - PMID: 35714604 - DOI: 10.1016/j.ccell.2022.05.016
Refining genetic and molecular classifications to facilitate breakthrough treatments in intrahepatic cholangiocarcinoma: are we there yet?
Gut. 2022;:ePub - PMID: 35772925 - DOI: 10.1136/gutjnl-2022-327782
Impact of renin-angiotensin system inhibitors on outcomes in patients with metastatic renal cell carcinoma treated with immune-checkpoint inhibitors
Clin Genitourin Cancer. 2022;20(4):301-306 - PMID: 35614012 - DOI: 10.1016/j.clgc.2022.04.012
Liver lymphatic drainage patterns follow segmental anatomy.
Br J Surg. 2022;109(6):559-560 - PMID: 35576376 - DOI: 10.1093/bjs/znac076
Multiphoton phosphorescence quenching microscopy reveals kinetics of tumor oxygenation during anti-angiogenesis and angiotensin signaling inhibition.
Clin Cancer Res. 2022;28(14):3076-3090 - PMID: 35584239 - DOI: 10.1158/1078-0432.CCR-22-0486
Solid stress impairs lymphocyte infiltration into lymph node metastases.
FASEB J. 2022;36 Suppl 1:ePub - PMID: 35557097 - DOI: 10.1096/fasebj.2022.36.S1.R4616
VCP interaction with HMGB1 promotes hepatocellular carcinoma progression by activating the PI3K/AKT/mTOR pathway.
Novel patient-derived xenograft and cell line models for therapeutic screening in NF2-associated schwannoma.
J Pathol. 2022;257(5):620-634 - PMID: 35394061 - DOI: 10.1002/path.5908
Gabrb3 endothelial cell-specific knockout mice display abnormal blood flow, hypertension, and behavioral dysfunction.
The effects of gravity and compression on interstitial fluid transport in the lower limb.
Increased CD8+ T-Cell Infiltration and Efficacy for Multikinase Inhibitors after PD-1 Blockade in Hepatocellular Carcinoma.
J Natl Cancer Inst. 2022;:ePub - PMID: 35288743 - DOI: 10.1093/jnci/djac051
Normalizing tumor microenvironment with nanomedicine and metronomic therapy to improve immunotherapy
Journal of Controlled Release. 2022;345:190-199 - PMID: 35271911 - PMCID: PMC9168447 - DOI: 10.1016/j.jconrel.2022.03.008
Towards principled design of cancer nanomedicine to accelerate clinical translation.
Mater Today Bio. 2022;13:100208 - PMID: 35198957 - PMCID: PMC8841842 - DOI: 10.1016/j.mtbio.2022.100208
Leveraging Blood-Based Diagnostics to Predict Tumor Biology and Extend the Application and Personalization of Radiotherapy in Liver Cancers.
Predictive Modeling of Survival and Toxicity in Patients With Hepatocellular Carcinoma After Radiotherapy.
JCO Clin Cancer Inform. 2022;6:e2100169 - PMID: 35192402 - PMCID: PMC8863122 - DOI: 10.1200/CCI.21.00169
Combining p53 mRNA nanotherapy with immune checkpoint blockade reprograms the immune microenvironment for effective cancer therapy.
Glycocalyx mechanotransduction mechanisms are involved in renal cancer metastasis.
Matrix Biol Plus. 2022;13:100100 - PMID: 35106474 - PMCID: PMC8789524 - DOI: 10.1016/j.mbplus.2021.100100
Renin–angiotensin–aldosterone system inhibitors and survival in patients with hypertension treated with immune checkpoint inhibitors
European Journal of Cancer. 2022;163:108-118 - PMID: 35065368 - DOI: 10.1016/j.ejca.2021.12.024
Strategies to minimize heterogeneity and optimize
clinical trials in Acute Respiratory Distress Syndrome
(ARDS): Insights from mathematical modelling
EBioMedicine. 2022;75:103809 - PMID: 35033853 - PMCID: PMC8757652 - DOI: 10.1016/j.ebiom.2021.103809
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