Huang Lab

Chen Y, Ramjiawan RR, Reiberger T, Ng MR, Hato T, Huang Y, Ochiai H, Kitahara S, Unan EC, Reddy TP, Fan C, Huang P, Bardeesy N, Zhu AX, Jain RK, Duda DG

CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice.
Hepatology. 2015;61(5):1591-602 - PMID: 25529917 - PMCID: PMC4406806 - DOI: 10.1002/hep.27665

Gao X, Zhao Y, Stemmer-Rachamimov AO, Liu H, Huang P, Chin S, Selig MK, Plotkin SR, Jain RK, Xu L

Anti-VEGF treatment improves neurological function and augments radiation response in NF2 schwannoma model.
Proc Natl Acad Sci U S A. 2015;112(47):14676-81 - PMID: 26554010 - PMCID: PMC4664377 - DOI: 10.1073/pnas.1512570112

Reiberger T, Chen Y, Ramjiawan RR, Hato T, Fan C, Samuel R, Roberge S, Huang P, Lauwers GY, Zhu AX, Bardeesy N, Jain RK, Duda DG

An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis.
Nat Protoc. 2015;10(8):1264-1274 - PMID: 26203823 - PMCID: PMC4800979 - DOI: 10.1038/nprot.2015.080

Zhang L, Li K, Sun R, Zhang Y, Ji J, Huang P, Yang H, Tian Y

Minocycline ameliorates cognitive impairment induced by whole-brain irradiation: an animal study.
Radiat Oncol. 2014;9(1):281 - PMID: 25498371 - PMCID: PMC4271325 - DOI: 10.1186/s13014-014-0281-8

Li W, Huang P, Chen DJ, Gerweck LE

Determinates of tumor response to radiation: Tumor cells, tumor stroma and permanent local control.
Radiother Oncol. 2014;113(1):146-9 - PMID: 25284063 - PMCID: PMC4280081 - DOI: 10.1016/j.radonc.2014.09.006

Wang Y, Li W, Patel SS, Cong J, Zhang N, Sabbatino F, Liu X, Qi Y, Huang P, Lee H, Taghian A, Li JJ, DeLeo AB, Ferrone S, Epperly MW, Ferrone CR, Ly A, Brachtel EF, Wang X

Blocking the formation of radiation-induced breast cancer stem cells.
Oncotarget. 2014;5(11):3743-55 - PMID: 25003837 - PMCID: PMC4116517 - DOI: 10.18632/oncotarget.1992

Chauhan VP, Martin JD, Liu H, Lacorre DA, Jain SR, Kozin SV, Stylianopoulos T, Mousa AS, Han X, Adstamongkonkul P, Popovic Z, Huang P, Bawendi MG, Boucher Y, Jain RK

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels.
Nat Commun. 2013;4:2516 - PMID: 24084631 - PMCID: PMC3806395 - DOI: 10.1038/ncomms3516

Huang Y, Yuan J, Righi E, Kamoun WS, Ancukiewicz M, Nezivar J, Santosuosso M, Martin JD, Martin MR, Vianello F, Leblanc P, Munn LL, Huang P, Duda DG, Fukumura D, Jain RK, Poznansky MC

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy.
Proc Natl Acad Sci U S A. 2012;109(43):17561-6 - PMID: 23045683 - PMCID: PMC3491458 - DOI: 10.1073/pnas.1215397109

Wang E, Feng Y, Zhang M, Zou L, Li Y, Buys ES, Huang P, Brouckaert P, Chao W

Toll-like receptor 4 signaling confers cardiac protection against ischemic injury via inducible nitric oxide synthase- and soluble guanylate cyclase-dependent mechanisms.
Anesthesiology. 2011;114(3):603-13 - PMID: 21270629 - PMCID: PMC3044772 - DOI: 10.1097/ALN.0b013e31820a4d5b

Liu J, Liao S, Huang Y, Samuel R, Shi T, Naxerova K, Huang P, Kamoun W, Jain RK, Fukumura D, Xu L

PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer.
Clin Cancer Res. 2011;17(11):3638-48 - PMID: 21459800 - PMCID: PMC3107920 - DOI: 10.1158/1078-0432.CCR-10-2456

Huang P, Westmoreland SV, Jain RK, Fukumura D

Spontaneous nonthymic tumors in SCID mice.
Comp Med. 2011;61(3):227-34 - PMID: 21819692 - PMCID: PMC3123755

Huang P, Duda DG, Jain RK, Fukumura D

Histopathologic findings and establishment of novel tumor lines from spontaneous tumors in FVB/N mice.
Comp Med. 2008;58(3):253-63 - PMID: 18589867 - PMCID: PMC2693079

Kozin SV, Niemierko A, Huang P, Silva J, Doppke KP, Suit HD

Inter- and intramouse heterogeneity of radiation response for a growing paired organ.
Radiat Res. 2008;170(2):264-7 - PMID: 18666813 - DOI: 10.1667/RR1262.1

Huang P, McKee TD, Jain RK, Fukumura D

Green fluorescent protein (GFP)-expressing tumor model derived from a spontaneous osteosarcoma in a vascular endothelial growth factor (VEGF)-GFP transgenic mouse.
Comp Med. 2005;55(3):236-43 - PMID: 16089171

Duda DG, Fukumura D, Munn LL, Booth MF, Brown EB, Huang P, Seed B, Jain RK

Differential transplantability of tumor-associated stromal cells.
Cancer Res. 2004;64(17):5920-4 - PMID: 15342367 - DOI: 10.1158/0008-5472.CAN-04-1268

Izumi Y, di Tomaso E, Hooper A, Huang P, Huber J, Hicklin DJ, Fukumura D, Jain RK, Suit HD

Responses to antiangiogenesis treatment of spontaneous autochthonous tumors and their isografts.
Cancer Res. 2003;63(4):747-51 - PMID: 12591719

Huang P, Olive PL, Durand RE

Use of the comet assay for assessment of drug resistance and its modulation in vivo.
Br J Cancer. 1998;77(3):412-6 - PMID: 9472636 - PMCID: PMC2151301 - DOI: 10.1038/bjc.1998.65

Huang P, Taghian A, Allam A, Freeman J, Duffy M, Suit H

The effect of whole-body irradiation of nude mice on the tumor transplantability and control probability of a human soft tissue sarcoma xenograft.
Radiat Res. 1996;145(3):337-42 - PMID: 8927702

Huang P, Taghian A, Hsu DW, Perez LA, Allam A, Duffy M, DaCosta A, Suit HD

Spontaneous metastasis, proliferation characteristics and radiation sensitivity of fractionated irradiation recurrent and unirradiated human xenografts.
Radiother Oncol. 1996;41(1):73-81 - PMID: 8961371 - DOI: 10.1016/s0167-8140(96)91803-4

Huang P, Suit HD

Spontaneous osteosarcoma in a severe combined immunodeficient (SCID/Sed) mouse.
Contemp Top Lab Anim Sci. 1996;35(6):75-7 - PMID: 16450991

Huang P, Allam A, Taghian A, Ruka W, Freeman J, Duffy M, Suit HD

Quantitative comparison of xenotransplantation of a human soft tissue sarcoma into the subcutaneous tissue of normal, postincision, and postincision plus indomethacin-treated nude mice.
J Surg Oncol. 1995;58(4):257-62 - PMID: 7723370 - DOI: 10.1002/jso.2930580412

Huang P, Allam A, Perez LA, Taghian A, Freeman J, Suit HD

The effect of combining recombinant human tumor necrosis factor-alpha with local radiation on tumor control probability of a human glioblastoma multiforme xenograft in nude mice.
Int J Radiat Oncol Biol Phys. 1995;32(1):93-8 - PMID: 7721643 - DOI: 10.1016/0360-3016(94)00492-4

Allam A, Perez LA, Huang P, Taghian A, Azinovic I, Freeman J, Duffy M, Efird J, Suit HD

The effect of the overall treatment time of fractionated irradiation on the tumor control probability of a human soft tissue sarcoma xenograft in nude mice.
Int J Radiat Oncol Biol Phys. 1995;32(1):105-11 - PMID: 7721606 - DOI: 10.1016/0360-3016(95)00511-V

Huang P, Allam A, Taghian A, Freeman J, Duffy M, Suit HD

Growth and metastatic behavior of five human glioblastomas compared with nine other histological types of human tumor xenografts in SCID mice.
J Neurosurg. 1995;83(2):308-15 - PMID: 7616277 - DOI: 10.3171/jns.1995.83.2.0308

Huang P

[Xenograft of human nasopharyngeal mucosa in nude mice].
Zhonghua Er Bi Yan Hou Ke Za Zhi. 1991;24(4):219-20, 255 - PMID: 2486076

Huang P

[Adult nasopharyngeal mucosa xenograft and dinitrosopiperazine carcinogenesis in nude mice].
Zhonghua Yi Xue Za Zhi. 1991;71(8):441-3, 32 - PMID: 1660764

Guan EN, Zhou TC, Wang JH, Chen Y, Sun YX, Huang PG, Tang WP, Zhao ML

Effects of monoclonal antibody anti-EGF receptor on human nasopharyngeal carcinoma cell and other tumor cells.
Sci China B. 1990;33(11):1334-40 - PMID: 2095159

Guan E, Zhou TC, Wang JH, Huang PG, Tang WP, Zhao ML, Chen Y, Sun YX

Growth inhibition of human nasopharyngeal carcinoma in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies.
Int J Cell Cloning. 1989;7(4):242-56 - PMID: 2768842 - DOI: 10.1002/stem.5530070406

Tang WP, Huang PG, Zhao ML, Liao SL, Zeng Y

Wikstroemia indica promotes development of nasopharyngeal carcinoma in rats initiated by dinitrosopiperazine.
J Cancer Res Clin Oncol. 1988;114(4):429-31 - PMID: 3410882 - PMCID: PMC12243837 - DOI: 10.1007/BF02128191
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