Ruscic KJ, Padera TP
Silence of the Lymphs: Some anaesthetic regimens inhibit lymphatic pumping.
J Physiol. 2019;597(11):2827-2828 - PMID: 31032908 - DOI: 10.1113/JP277914
Seano G, Nia HT, Emblem KE, Datta M, Ren J, Krishnan S, Kloepper J, Pinho MC, Ho WW, Ghosh M, Askoxylakis V, Ferraro GB, Riedemann L, Gerstner ER, Batchelor TT, Wen PY, Lin NU, Grodzinsky AJ, Fukumura D, Huang P, Baish JW, Padera TP, Munn LL, Jain RK
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium.
Nat Biomed Eng. 2019;3(3):230-245 - PMID: 30948807 - DOI: 10.1038/s41551-018-0334-7
Johnson AR, Granoff MD, Lee BT, Padera TP, Bouta EM, Singhal D
The Impact of Taxane-based Chemotherapy on the Lymphatic System.
Ann Plast Surg. 2019;82(4S Suppl 3):S173-S178 - PMID: 30855384 - DOI: 10.1097/SAP.0000000000001884
Liao S, Bouta EM, Morris LM, Jones D, Jain RK, Padera TP
Inducible Nitric Oxide Synthase and CD11b<sup>+</sup>Gr1<sup>+</sup> Cells Impair Lymphatic Contraction of Tumor-Draining Lymphatic Vessels.
Lymphat Res Biol. 2018;17(3):294-300 - PMID: 30358484 - DOI: 10.1089/lrb.2018.0013
Nathanson SD, Krag D, Kuerer HM, Newman LA, Brown M, Kerjaschki D, Pereira ER, Padera TP
Breast cancer metastasis through the lympho-vascular system.
Clin Exp Metastasis. 2018;35(5-6):443-454 - PMID: 29796854 - DOI: 10.1007/s10585-018-9902-1
Bourquard A, Pablo-Trinidad A, Butterworth I, Sánchez-Ferro Á, Cerrato C, Humala K, Fabra Urdiola M, Del Rio C, Valles B, Tucker-Schwartz JM, Lee ES, Vakoc BJ, Padera TP, Ledesma-Carbayo MJ, Chen YB, Hochberg EP, Gray ML, Castro-González C
Non-invasive detection of severe neutropenia in chemotherapy patients by optical imaging of nailfold microcirculation.
Sci Rep. 2018;8(1):5301 - PMID: 29593221 - PMCID: PMC5871877 - DOI: 10.1038/s41598-018-23591-0
Pereira ER, Kedrin D, Seano G, Gautier O, Meijer EFJ, Jones D, Chin SM, Kitahara S, Bouta EM, Chang J, Beech E, Jeong HS, Carroll MC, Taghian AG, Padera TP
Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice.
Science. 2018;359(6382):1403-1407 - PMID: 29567713 - PMCID: PMC6002772 - DOI: 10.1126/science.aal3622
Jones D, Pereira ER, Padera TP
Growth and Immune Evasion of Lymph Node Metastasis.
Front Oncol. 2018;8:36 - PMID: 29527513 - PMCID: PMC5829610 - DOI: 10.3389/fonc.2018.00036
Bouta EM, Blatter C, Ruggieri TA, Meijer EF, Munn LL, Vakoc BJ, Padera TP
Lymphatic function measurements influenced by contrast agent volume and body position.
JCI Insight. 2018;3(2):ePub - PMID: 29367467 - PMCID: PMC5821192 - DOI: 10.1172/jci.insight.96591
Jones D, Meijer EFJ, Blatter C, Liao S, Pereira ER, Bouta EM, Jung K, Chin SM, Huang P, Munn LL, Vakoc BJ, Otto M, Padera TP
Methicillin-resistant Staphylococcus aureus causes sustained collecting lymphatic vessel dysfunction.
Sci Transl Med. 2018;10(424):ePub - PMID: 29343625 - PMCID: PMC5953194 - DOI: 10.1126/scitranslmed.aam7964
Lippok N, Villiger M, Albanese A, Meijer EFJ, Chung K, Padera TP, Bhatia SN, Bouma BE
Depolarization signatures map gold nanorods within biological tissue.
Nat Photonics. 2017;11:583-588 - PMID: 29201136 - PMCID: PMC5703429 - DOI: 10.1038/nphoton.2017.128
Jung K, Heishi T, Incio J, Huang Y, Beech EY, Pinter M, Ho WW, Kawaguchi K, Rahbari NN, Chung E, Kim JK, Clark JW, Willett CG, Yun SH, Luster AD, Padera TP, Jain RK, Fukumura D
Targeting CXCR4-dependent immunosuppressive Ly6C(low) monocytes improves antiangiogenic therapy in colorectal cancer.
Proc Natl Acad Sci U S A. 2017;114(39):10455-10460 - PMID: 28900008 - PMCID: PMC5625928 - DOI: 10.1073/pnas.1710754114
Blatter C, Meijer EFJ, Padera TP, Vakoc BJ
Simultaneous measurements of lymphatic vessel contraction, flow and valve dynamics in multiple lymphangions using optical coherence tomography.
J Biophotonics. 2017;11(8):e201700017 - PMID: 28700145 - PMCID: PMC5766440 - DOI: 10.1002/jbio.201700017
Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy.
J Clin Invest. 2017;127(8):3039-3051 - PMID: 28691930 - PMCID: PMC5531423 - DOI: 10.1172/JCI93182
Meijer EFJ, Jeong HS, Pereira ER, Ruggieri TA, Blatter C, Vakoc BJ, Padera TP
Murine chronic lymph node window for longitudinal intravital lymph node imaging.
Nat Protoc. 2017;12(8):1513-1520 - PMID: 28683064 - PMCID: PMC5592697 - DOI: 10.1038/nprot.2017.045
Meijer EF, Blatter C, Chen IX, Bouta E, Jones D, Pereira ER, Jung K, Vakoc BJ, Baish JW, Padera TP
Lymph node effective vascular permeability and chemotherapy uptake.
Microcirculation. 2017;24(6):ePub - PMID: 28510992 - PMCID: PMC5706450 - DOI: 10.1111/micc.12381
Nia HT, Liu H, Seano G, Datta M, Jones D, Rahbari N, Incio J, Chauhan VP, Jung K, Martin JD, Askoxylakis V, Padera TP, Fukumura D, Boucher Y, Hornicek FJ, Grodzinsky AJ, Baish JW, Munn LL, Jain RK
Solid stress and elastic energy as measures of tumour mechanopathology.
Nat Biomed Eng. 2016;1:ePub - PMID: 28966873 - PMCID: PMC5621647 - DOI: 10.1038/s41551-016-0004
Baish JW, Kunert C, Padera TP, Munn LL
Synchronization and Random Triggering of Lymphatic Vessel Contractions.
PLoS Comput Biol. 2016;12(12):e1005231 - PMID: 27935958 - PMCID: PMC5147819 - DOI: 10.1371/journal.pcbi.1005231
Meijer EF, Baish JW, Padera TP, Fukumura D
Measuring Vascular Permeability In Vivo.
Methods Mol Biol. 2016;1458:71-85 - PMID: 27581015 - PMCID: PMC5435480 - DOI: 10.1007/978-1-4939-3801-8_6
Blatter C, Meijer EF, Nam AS, Jones D, Bouma BE, Padera TP, Vakoc BJ
In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography.
Sci Rep. 2016;6:29035 - PMID: 27377852 - PMCID: PMC4932526 - DOI: 10.1038/srep29035
Padera TP, Meijer EF, Munn LL
The Lymphatic System in Disease Processes and Cancer Progression.
Annu Rev Biomed Eng. 2016;18:125-58 - PMID: 26863922 - PMCID: PMC4946986 - DOI: 10.1146/annurev-bioeng-112315-031200
Kunert C, Baish JW, Liao S, Padera TP, Munn LL
Reply to Davis: Nitric oxide regulates lymphatic contractions.
Proc Natl Acad Sci U S A. 2015;113(2):E106 - PMID: 26719425 - PMCID: PMC4720299 - DOI: 10.1073/pnas.1522233113
Jeong HS, Jones D, Liao S, Wattson DA, Cui CH, Duda DG, Willett CG, Jain RK, Padera TP
Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases.
J Natl Cancer Inst. 2015;107(9):ePub - PMID: 26063793 - PMCID: PMC4651102 - DOI: 10.1093/jnci/djv155
Kesler CT, Pereira ER, Cui CH, Nelson GM, Masuck DJ, Baish JW, Padera TP
Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation.
FASEB J. 2015;29(9):3668-77 - PMID: 25977256 - PMCID: PMC4550378 - DOI: 10.1096/fj.14-268920
Cho JK, Hyun SH, Choi N, Kim MJ, Padera TP, Choi JY, Jeong HS
Significance of lymph node metastasis in cancer dissemination of head and neck cancer.
Transl Oncol. 2015;8(2):119-25 - PMID: 25926078 - PMCID: PMC4415144 - DOI: 10.1016/j.tranon.2015.03.001
Padera TP
Editorial.
Semin Cell Dev Biol. 2015;38:53-4 - PMID: 25868083 - DOI: 10.1016/j.semcdb.2015.03.007
Ladra MM, Mandeville HC, Niemierko A, Padera TP, Friedmann AM, MacDonald SM, Ebb D, Chen YL, Tarbell NJ, Yock TI
Local Failure in Parameningeal Rhabdomyosarcoma Correlates With Poor Response to Induction Chemotherapy.
Int J Radiat Oncol Biol Phys. 2015;92(2):358-67 - PMID: 25864172 - PMCID: PMC5479480 - DOI: 10.1016/j.ijrobp.2015.01.049
Pereira ER, Jones D, Jung K, Padera TP
The lymph node microenvironment and its role in the progression of metastatic cancer.
Semin Cell Dev Biol. 2015;38:98-105 - PMID: 25620792 - PMCID: PMC4397158 - DOI: 10.1016/j.semcdb.2015.01.008
Kuo AH, Ancukiewicz M, Kozak KR, Yock TI, Padera TP
Cardiac and inflammatory biomarkers do not correlate with volume of heart or lung receiving radiation.
Radiat Oncol. 2015;10(1):5 - PMID: 25573181 - PMCID: PMC4293110 - DOI: 10.1186/s13014-014-0324-1
Liao S, Jones D, Cheng G, Padera TP
Method for the quantitative measurement of collecting lymphatic vessel contraction in mice.
J Biol Methods. 2014;1(2):ePub - PMID: 25512945 - PMCID: PMC4264607 - DOI: 10.14440/jbm.2014.26
Chauhan VP, Boucher Y, Ferrone CR, Roberge S, Martin JD, Stylianopoulos T, Bardeesy N, DePinho RA, Padera TP, Munn LL, Jain RK
Compression of Pancreatic Tumor Blood Vessels by Hyaluronan Is Caused by Solid Stress and Not Interstitial Fluid Pressure.
Cancer Cell. 2014;26(1):14-15 - PMID: 25026209 - PMCID: PMC4381566 - DOI: 10.1016/j.ccr.2014.06.003
Munn LL, Padera TP
Imaging the Lymphatic System.
Microvasc Res. 2014;96C:55-63 - PMID: 24956510 - PMCID: PMC4268344 - DOI: 10.1016/j.mvr.2014.06.006
Hagendoorn J, Yock TI, Borel Rinkes IH, Padera TP, Ebb DH
Novel molecular pathways in Gorham disease: Implications for treatment.
Pediatr Blood Cancer. 2013;61(3):401-6 - PMID: 24214028 - PMCID: PMC4123459 - DOI: 10.1002/pbc.24832
Kesler CT, Kuo AH, Wong HK, Masuck DJ, Shah JL, Kozak KR, Held KD, Padera TP
Vascular endothelial growth factor-C enhances radiosensitivity of lymphatic endothelial cells.
Angiogenesis. 2013;17(2):419-27 - PMID: 24201897 - PMCID: PMC3981926 - DOI: 10.1007/s10456-013-9400-7
Liao S, Padera TP
Lymphatic Function and Immune Regulation in Health and Disease.
Lymphat Res Biol. 2013;11(3):136-43 - PMID: 24024577 - PMCID: PMC3780287 - DOI: 10.1089/lrb.2013.0012
Goel S, Gupta N, Walcott BP, Snuderl M, Kesler CT, Kirkpatrick ND, Heishi T, Huang Y, Martin JD, Ager E, Samuel R, Wang S, Yazbek J, Vakoc BJ, Peterson RT, Padera TP, Duda DG, Fukumura D, Jain RK
Effects of Vascular-Endothelial Protein Tyrosine Phosphatase Inhibition on Breast Cancer Vasculature and Metastatic Progression.
J Natl Cancer Inst. 2013;105(16):1188-1201 - PMID: 23899555 - PMCID: PMC3748004 - DOI: 10.1093/jnci/djt164
Kirkpatrick ND, Chung E, Cook DC, Han X, Gruionu G, Liao S, Munn LL, Padera TP, Fukumura D, Jain RK
Video-rate resonant scanning multiphoton microscopy: An emerging technique for intravital imaging of the tumor microenvironment.
Intravital. 2012;1(1):ePub - PMID: 24353926 - PMCID: PMC3864876 - DOI: 10.4161/intv.21557
Kesler CT, Liao S, Munn LL, Padera TP
Lymphatic vessels in health and disease.
Wiley Interdiscip Rev Syst Biol Med. 2012;5(1):111-24 - PMID: 23209022 - PMCID: PMC3527689 - DOI: 10.1002/wsbm.1201
Liao S, Cheng G, Conner DA, Huang Y, Kucherlapati RS, Munn LL, Ruddle NH, Jain RK, Fukumura D, Padera TP
Impaired lymphatic contraction associated with immunosuppression.
Proc Natl Acad Sci U S A. 2011;108(46):18784-9 - PMID: 22065738 - PMCID: PMC3219138 - DOI: 10.1073/pnas.1116152108
Liao S, Padera TP, Jain RK
Notch leads lymphatics and links them to blood vessels.
Arterioscler Thromb Vasc Biol. 2010;30(9):1682-3 - PMID: 20720193 - PMCID: PMC2945915 - DOI: 10.1161/ATVBAHA.110.210633
Mounzer RH, Svendsen OS, Baluk P, Bergman CM, Padera TP, Wiig H, Jain RK, McDonald DM, Ruddle NH
Lymphotoxin-alpha contributes to lymphangiogenesis.
Blood. 2010;116(12):2173-82 - PMID: 20566898 - PMCID: PMC2951858 - DOI: 10.1182/blood-2009-12-256065
Lahdenranta J, Hagendoorn J, Padera TP, Hoshida T, Nelson G, Kashiwagi S, Jain RK, Fukumura D
Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis.
Cancer Res. 2009;69(7):2801-8 - PMID: 19318557 - PMCID: PMC2670480 - DOI: 10.1158/0008-5472.CAN-08-4051
Chauhan VP, Lanning RM, Diop-Frimpong B, Mok W, Brown EB, Padera TP, Boucher Y, Jain RK
Multiscale measurements distinguish cellular and interstitial hindrances to diffusion in vivo.
Biophys J. 2009;97(1):330-6 - PMID: 19580771 - PMCID: PMC2711376 - DOI: 10.1016/j.bpj.2009.03.064
Vakoc BJ, Lanning RM, Tyrrell JA, Padera TP, Bartlett LA, Stylianopoulos T, Munn LL, Tearney GJ, Fukumura D, Jain RK, Bouma BE
Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging.
Nat Med. 2009;15(10):1219-23 - PMID: 19749772 - PMCID: PMC2759417 - DOI: 10.1038/nm.1971
Luong MX, Tam J, Lin Q, Hagendoorn J, Moore KJ, Padera TP, Seed B, Fukumura D, Kucherlapati R, Jain RK
Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice.
J Cell Physiol. 2009;219(2):430-7 - PMID: 19170073 - PMCID: PMC2665001 - DOI: 10.1002/jcp.21686
Plotkin SR, Stemmer-Rachamimov AO, Barker FG, Halpin C, Padera TP, Tyrrell A, Sorensen AG, Jain RK, di Tomaso E
Hearing improvement after bevacizumab in patients with neurofibromatosis type 2.
N Engl J Med. 2009;361(4):358-67 - PMID: 19587327 - PMCID: PMC4816642 - DOI: 10.1056/NEJMoa0902579
Perentes JY, McKee TD, Ley CD, Mathiew H, Dawson M, Padera TP, Munn LL, Jain RK, Boucher Y
In vivo imaging of extracellular matrix remodeling by tumor-associated fibroblasts.
Nat Methods. 2009;6(2):143-5 - PMID: 19151720 - PMCID: PMC2877598 - DOI: 10.1038/nmeth.1295
Jain RK, Booth MF, Padera TP, Munn LL, Fukumura D, Brown E
Applications of nonlinear intravital microscopy in tumor biology.
In: Handbook of Biomedical Nonlinear Optical Microscopy (Editors: B. R. Masters and P. T. C. So). Oxford University Press, New York. 2008;Chapter 29:735-756
Padera TP, Jain RK
VEGFR3: a new target for antiangiogenesis therapy?
Dev Cell. 2008;15(2):178-9 - PMID: 18694556 - PMCID: PMC4790102 - DOI: 10.1016/j.devcel.2008.07.014
Padera TP, Kuo AH, Hoshida T, Liao S, Lobo J, Kozak KR, Fukumura D, Jain RK
Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib.
Mol Cancer Ther. 2008;7(8):2272-9 - PMID: 18687659 - PMCID: PMC2664998 - DOI: 10.1158/1535-7163.MCT-08-0182
Padera TP, Ancukiewicz M, Hoshida T, Fukumura D, Jain RK
Data do not support benefits of anti-VEGFR3 therapy
Cancer Research. 2007;67:5055
Nelson GM, Padera TP, Garkavtsev I, Shioda T, Jain RK
Differential gene expression of primary cultured lymphatic and blood vascular endothelial cells.
Neoplasia. 2007;9(12):1038-45 - PMID: 18084611 - PMCID: PMC2137938
Padera TP, Ancukiewicz M, Hoshida T, Fukumura D, Jain RK
Anti-VEGFR-3 therapy and lymph node metastasis [corrected].
Cancer Res. 2007;67(10):5055; author reply 5056 - PMID: 17510438 - DOI: 10.1158/0008-5472.CAN-06-2935
Hagendoorn J, Tong R, Fukumura D, Lin Q, Lobo J, Padera TP, Xu L, Kucherlapati R, Jain RK
Onset of abnormal blood and lymphatic vessel function and interstitial hypertension in early stages of carcinogenesis.
Cancer Res. 2006;66(7):3360-4 - PMID: 16585153 - DOI: 10.1158/0008-5472.CAN-05-2655
Hagendoorn J, Padera TP, Yock TI, Nielsen GP, di Tomaso E, Duda DG, Delaney TF, Gaissert HA, Pearce J, Rosenberg AE, Jain RK, Ebb DH
Platelet-derived growth factor receptor-beta in Gorham's disease.
Nat Clin Pract Oncol. 2006;3(12):693-7 - PMID: 17139320 - PMCID: PMC2693369 - DOI: 10.1038/ncponc0660
Hoon DS, Kitago M, Kim J, Mori T, Piris A, Szyfelbein K, Mihm MC, Nathanson SD, Padera TP, Chambers AF, Vantyghem SA, MacDonald IC, Shivers SC, Alsarraj M, Reintgen DS, Passlick B, Sienel W, Pantel K
Molecular mechanisms of metastasis.
Cancer Metastasis Rev. 2006;25(2):203-20 - PMID: 16770533 - DOI: 10.1007/s10555-006-8500-x
Hoshida T, Isaka N, Hagendoorn J, di Tomaso E, Chen YL, Pytowski B, Fukumura D, Padera TP, Jain RK
Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications.
Cancer Res. 2006;66(16):8065-75 - PMID: 16912183 - DOI: 10.1158/0008-5472.CAN-06-1392
Hagendoorn J, Padera TP, Fukumura D, Jain RK
Molecular regulation of microlymphatic formation and function: role of nitric oxide.
Trends Cardiovasc Med. 2005;15(5):169-73 - PMID: 16165013 - DOI: 10.1016/j.tcm.2005.06.003
Isaka N, Padera TP, Hagendoorn J, Fukumura D, Jain RK
Peritumor lymphatics induced by vascular endothelial growth factor-C exhibit abnormal function.
Cancer Res. 2004;64(13):4400-4 - PMID: 15231646 - DOI: 10.1158/0008-5472.CAN-04-0752
Padera TP, Stoll BR, Tooredman JB, Capen D, di Tomaso E, Jain RK
Pathology: cancer cells compress intratumour vessels.
Nature. 2004;427(6976):695 - PMID: 14973470 - DOI: 10.1038/427695a
Hagendoorn J, Padera TP, Kashiwagi S, Isaka N, Noda F, Lin MI, Huang PL, Sessa WC, Fukumura D, Jain RK
Endothelial nitric oxide synthase regulates microlymphatic flow via collecting lymphatics.
Circ Res. 2004;95(2):204-9 - PMID: 15192027 - DOI: 10.1161/01.RES.0000135549.72828.24
Padera TP, Stoll BR, So PT, Jain RK
Conventional and high-speed intravital multiphoton laser scanning microscopy of microvasculature, lymphatics, and leukocyte-endothelial interactions.
Mol Imaging. 2003;1(1):9-15 - PMID: 12920856
Padera TP, Boucher Y, Jain RK
Correspondence re: S. Maula et al., intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinoma of the head and neck. Cancer Res., 63: 1920-1926, 2003.
Cancer Res. 2003;63(23):8555-6; author reply 8558 - PMID: 14679026
Jain RK, Padera TP
Development. Lymphatics make the break.
Science. 2003;299(5604):209-10 - PMID: 12522236 - DOI: 10.1126/science.1081345
Padera TP, Kadambi A, di Tomaso E, Carreira CM, Brown EB, Boucher Y, Choi NC, Mathisen D, Wain J, Mark EJ, Munn LL, Jain RK
Lymphatic metastasis in the absence of functional intratumor lymphatics.
Science. 2002;296(5574):1883-6 - PMID: 11976409 - DOI: 10.1126/science.1071420
Jain RK, Padera TP
Prevention and treatment of lymphatic metastasis by antilymphangiogenic therapy.
J Natl Cancer Inst. 2002;94(11):785-7 - PMID: 12048260
Kadambi A, Mouta Carreira C, Yun CO, Padera TP, Dolmans DE, Carmeliet P, Fukumura D, Jain RK
Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: role of VEGF-receptor 2 and host VEGF-A.
Cancer Res. 2001;61(6):2404-8 - PMID: 11289105
Mouta Carreira C, Nasser SM, di Tomaso E, Padera TP, Boucher Y, Tomarev SI, Jain RK
LYVE-1 is not restricted to the lymph vessels: expression in normal liver blood sinusoids and down-regulation in human liver cancer and cirrhosis.
Cancer Res. 2001;61(22):8079-84 - PMID: 11719431
Ramanujan S, Koenig GC, Padera TP, Stoll BR, Jain RK
Local imbalance of proangiogenic and antiangiogenic factors: a potential mechanism of focal necrosis and dormancy in tumors.
Cancer Res. 2000;60(5):1442-8 - PMID: 10728711
Hansen-Algenstaedt N, Stoll BR, Padera TP, Dolmans DE, Hicklin DJ, Fukumura D, Jain RK
Tumor oxygenation in hormone-dependent tumors during vascular endothelial growth factor receptor-2 blockade, hormone ablation, and chemotherapy.
Cancer Res. 2000;60(16):4556-60 - PMID: 10969807
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