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Baish JW, Netti PA, Jain RK
Transmural coupling of fluid flow in microcirculatory network and interstitium in tumors.
Microvasc Res. 1997;53(2):128-41 - PMID: 9143544 - DOI: 10.1006/mvre.1996.2005
Leunig M, Yuan F, Gerweck LE, Jain RK
Effect of basic fibroblast growth factor on angiogenesis and growth of isografted bone: quantitative in vitro-in vivo analysis in mice.
Int J Microcirc Clin Exp. 1997;17(1):1-9 - PMID: 9176719 - DOI: 10.1159/000179199
Helmlinger G, Netti PA, Lichtenbeld HC, Melder RJ, Jain RK
Solid stress inhibits the growth of multicellular tumor spheroids.
Nat Biotechnol. 1997;15(8):778-83 - PMID: 9255794 - DOI: 10.1038/nbt0897-778
Nozue M, Lee I, Yuan F, Teicher BA, Brizel DM, Dewhirst MW, Milross CG, Milas L, Song CW, Thomas CD, Guichard M, Evans SM, Koch CJ, Lord EM, Jain RK, Suit HD
Interlaboratory variation in oxygen tension measurement by Eppendorf "Histograph" and comparison with hypoxic marker.
J Surg Oncol. 1997;66(1):30-8 - PMID: 9290690 - DOI: 10.1002/(sici)1096-9098(199709)66:1<30::aid-jso7>3.0.co;2-o
Griffon-Etienne G, Boucher Y, Jain RK, Suit HD
Effects of needle insertion in tumors on interstitial fluid pressure.
Microvasc Res. 1997;54(2):174-7 - PMID: 9327388 - DOI: 10.1006/mvre.1997.2037
Jain RK, Schlenger K, Höckel M, Yuan F
Quantitative angiogenesis assays: progress and problems.
Nat Med. 1997;3(11):1203-8 - PMID: 9359693 - DOI: 10.1038/nm1197-1203
Gazit Y, Baish JW, Safabakhsh N, Leunig M, Baxter LT, Jain RK
Fractal characteristics of tumor vascular architecture during tumor growth and regression.
Microcirculation. 1997;4(4):395-402 - PMID: 9431507 - DOI: 10.3109/10739689709146803
Zhu H, Jain RK, Baxter LT
Tumor pretargeting for radioimmunodetection and radioimmunotherapy.
J Nucl Med. 1998;39(1):65-76 - PMID: 9443740
Hobbs SK, Monsky WL, Yuan F, Roberts WG, Griffith L, Torchilin VP, Jain RK
Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment.
Proc Natl Acad Sci U S A. 1998;95(8):4607-12 - PMID: 9539785 - PMCID: PMC22537 - DOI: 10.1073/pnas.95.8.4607
Hunter GJ, Hamberg LM, Choi N, Jain RK, McCloud T, Fischman AJ
Dynamic T1-weighted magnetic resonance imaging and positron emission tomography in patients with lung cancer: correlating vascular physiology with glucose metabolism.
Clin Cancer Res. 1998;4(4):949-55 - PMID: 9563889
Schoepf U, Marecos EM, Melder RJ, Jain RK, Weissleder R
Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies.
Biotechniques. 1998;24(4):642-6, 648-51 - PMID: 9564539 - DOI: 10.2144/98244rr01
Rosenzweig M, DeMaria MA, Harper DM, Friedrich S, Jain RK, Johnson RP
Increased rates of CD4(+) and CD8(+) T lymphocyte turnover in simian immunodeficiency virus-infected macaques.
Proc Natl Acad Sci U S A. 1998;95(11):6388-93 - PMID: 9600975 - PMCID: PMC27734 - DOI: 10.1073/pnas.95.11.6388
Jain RK
Integrative pathophysiology of solid tumors: role in detection and treatment.
Cancer J Sci Am. 1998;4 Suppl 1:S48-57 - PMID: 9619271
Jain RK
The next frontier of molecular medicine: delivery of therapeutics.
Nat Med. 1998;4(6):655-7 - PMID: 9623964 - DOI: 10.1038/nm0698-655
Jain RK, Safabakhsh N, Sckell A, Chen Y, Jiang P, Benjamin L, Yuan F, Keshet E
Endothelial cell death, angiogenesis, and microvascular function after castration in an androgen-dependent tumor: role of vascular endothelial growth factor.
Proc Natl Acad Sci U S A. 1998;95(18):10820-5 - PMID: 9724788 - PMCID: PMC27979 - DOI: 10.1073/pnas.95.18.10820
Baish JW, Jain RK
Cancer, angiogenesis and fractals.
Nat Med. 1998;4(9):984 - PMID: 9734370 - DOI: 10.1038/1952
Jain RK
Delivery of molecular and cellular medicine to solid tumors.
J Control Release. 1998;53(1-3):49-67 - PMID: 9741913 - DOI: 10.1016/s0168-3659(97)00237-x
Kristjansen PE, Brown TJ, Shipley LA, Jain RK
Intratumor pharmacokinetics, flow resistance, and metabolism during gemcitabine infusion in ex vivo perfused human small cell lung cancer.
Clin Cancer Res. 1996;2(2):359-67 - PMID: 9816179
Sckell A, Safabakhsh N, Dellian M, Jain RK
Primary tumor size-dependent inhibition of angiogenesis at a secondary site: an intravital microscopic study in mice.
Cancer Res. 1998;58(24):5866-9 - PMID: 9865747
Kristensen CA, Askenasy N, Jain RK, Koretsky AP
Creatine and cyclocreatine treatment of human colon adenocarcinoma xenografts: 31P and 1H magnetic resonance spectroscopic studies.
Br J Cancer. 1999;79(2):278-85 - PMID: 9888469 - PMCID: PMC2362210 - DOI: 10.1038/sj.bjc.6690045
Kristensen CA, Roberge S, Jain RK
Effect of tumor necrosis factor alpha on vascular resistance, nitric oxide production, and glucose and oxygen consumption in perfused tissue-isolated human melanoma xenografts.
Clin Cancer Res. 1997;3(3):319-24 - PMID: 10026014
Slavin SA, Van den Abbeele AD, Losken A, Swartz MA, Jain RK
Return of lymphatic function after flap transfer for acute lymphedema.
Ann Surg. 1999;229(3):421-7 - PMID: 10077056 - PMCID: PMC1191709 - DOI: 10.1097/00000658-199903000-00017
Moulton KS, Melder RJ, Dharnidharka VR, Hardin-Young J, Jain RK, Briscoe DM
Angiogenesis in the huPBL-SCID model of human transplant rejection.
Transplantation. 1999;67(12):1626-31 - PMID: 10401773 - DOI: 10.1097/00007890-199906270-00020
Jain RK
Understanding barriers to drug delivery: high resolution in vivo imaging is key.
Clin Cancer Res. 1999;5(7):1605-6 - PMID: 10430057
Endo M, Jain RK, Witwer B, Brown D
Water channel (aquaporin 1) expression and distribution in mammary carcinomas and glioblastomas.
Microvasc Res. 1999;58(2):89-98 - PMID: 10458924 - DOI: 10.1006/mvre.1999.2158
Heijn M, Roberge S, Jain RK
Cellular membrane permeability of anthracyclines does not correlate with their delivery in a tissue-isolated tumor.
Cancer Res. 1999;59(17):4458-63 - PMID: 10485498
Hashizume H, Baluk P, Morikawa S, McLean JW, Thurston G, Roberge S, Jain RK, McDonald DM
Openings between defective endothelial cells explain tumor vessel leakiness.
Am J Pathol. 2000;156(4):1363-80 - PMID: 10751361 - PMCID: PMC1876882 - DOI: 10.1016/S0002-9440(10)65006-7
Dellian M, Yuan F, Trubetskoy VS, Torchilin VP, Jain RK
Vascular permeability in a human tumour xenograft: molecular charge dependence.
Br J Cancer. 2000;82(9):1513-8 - PMID: 10789717 - PMCID: PMC2363402 - DOI: 10.1054/bjoc.1999.1171
Netti PA, Berk DA, Swartz MA, Grodzinsky AJ, Jain RK
Role of extracellular matrix assembly in interstitial transport in solid tumors.
Cancer Res. 2000;60(9):2497-503 - PMID: 10811131
Helmlinger G, Endo M, Ferrara N, Hlatky L, Jain RK
Formation of endothelial cell networks.
Nature. 2000;405(6783):139-41 - PMID: 10821260 - DOI: 10.1038/35012132
Baish JW, Jain RK
Fractals and cancer.
Cancer Res. 2000;60(14):3683-8 - PMID: 10919633
Kristensen CA, Hamberg LM, Hunter GJ, Roberge S, Kierstead D, Wolf GL, Jain RK
Changes in vascularization of human breast cancer xenografts responding to antiestrogen therapy.
Neoplasia. 1999;1(6):518-25 - PMID: 10935499 - PMCID: PMC1508121 - DOI: 10.1038/sj.neo.7900063
Leu AJ, Berk DA, Lymboussaki A, Alitalo K, Jain RK
Absence of functional lymphatics within a murine sarcoma: a molecular and functional evaluation.
Cancer Res. 2000;60(16):4324-7 - PMID: 10969769
Carmeliet P, Jain RK
Angiogenesis in cancer and other diseases.
Nature. 2000;407(6801):249-57 - PMID: 11001068 - DOI: 10.1038/35025220
Jain RK
Delivery of molecular and cellular medicine to solid tumors.
Adv Drug Deliv Rev. 2001;46(1-3):149-68 - PMID: 11259838 - DOI: 10.1016/s0169-409x(00)00131-9
Jain RK
Clearing the smoke on nicotine and angiogenesis.
Nat Med. 2001;7(7):775-7 - PMID: 11433337 - DOI: 10.1038/89889
Jain RK
Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function.
J Control Release. 2001;74(1-3):7-25 - PMID: 11489479 - DOI: 10.1016/s0168-3659(01)00306-6
Jain RK
Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy.
Nat Med. 2001;7(9):987-9 - PMID: 11533692 - DOI: 10.1038/nm0901-987
Jain RK
Transport of molecules, particles, and cells in solid tumors.
Annu Rev Biomed Eng. 2001;1:241-63 - PMID: 11701489 - DOI: 10.1146/annurev.bioeng.1.1.241
Jain RK, Forbes NS
Can engineered bacteria help control cancer?
Proc Natl Acad Sci U S A. 2001;98(26):14748-50 - PMID: 11752416 - PMCID: PMC64926 - DOI: 10.1073/pnas.261606598
Jain RK, Carmeliet PF
Vessels of death or life.
Sci Am. 2001;285(6):38-45 - PMID: 11759584 - DOI: 10.1038/scientificamerican1201-38
Davies Cde L, Berk DA, Pluen A, Jain RK
Comparison of IgG diffusion and extracellular matrix composition in rhabdomyosarcomas grown in mice versus in vitro as spheroids reveals the role of host stromal cells.
Br J Cancer. 2002;86(10):1639-44 - PMID: 12085216 - PMCID: PMC2746604 - DOI: 10.1038/sj.bjc.6600270
Jain RK
Angiogenesis and lymphangiogenesis in tumors: insights from intravital microscopy.
Cold Spring Harb Symp Quant Biol. 2003;67:239-48 - PMID: 12858546 - DOI: 10.1101/sqb.2002.67.239
Jain RK, Wei J, Gullino PM
Pharmacokinetics of methotrexate in solid tumors.
J Pharmacokinet Biopharm. 1979;7(2):181-94 - PMID: 20218013 - DOI: 10.1007/BF01059737
Ivanov B, Dimitrov DS, Somasundaran P, Jain RK
Thinning of films with deformable surfaces: diffusion-controlled surfactant transfer
Chemical Engineering Science. 1985;40:137-150
Ruckenstein E, Jain RK
Spontaneous rupture of thin liquid films
J Chemical Society, Faraday Transactions II. 1974;70:132-147
Jain RK, Ruckenstein E
Stability of stagnant viscous films on a solid surface
J Colloid and Interface Science. 1976;54:108-116
Jain RK, Denn MM
Short term regulation of BOD upsets in an estuary
Trans. ASME J. Dynamic Systems, Measurement and Control. 1976;98, Series G:30-31
Jain RK, Wei J
Dynamics of drug transport in solid tumors: distributed parameter model
J Bioengineering. 1977;1:313-329
Sien HP, Jain RK
Temperature distributions in normal and neoplastic tissues during hyperthermia: a lumped parameter model
J Thermal Biology. 1979;4:157-164
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