Steele Labs :: Publications

Lefter LP, Furukawa T, Sunamura M, Duda DG, Takeda K, Kotobuki N, Oshimura M, Matsuno S, Horii A

Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines.

Genes Chromosomes Cancer. 2002;34(2):234-42 - PMID: 11979557 - DOI: 10.1002/gcc.10060

Sunamura M, Yatsuoka T, Motoi F, Duda DG, Kimura M, Abe T, Yokoyama T, Inoue H, Oonuma M, Takeda K, Matsuno S

Gene therapy for pancreatic cancer based on genetic characterization of the disease.

J Hepatobiliary Pancreat Surg. 2002;9(1):32-8 - PMID: 12021895 - DOI: 10.1007/s005340200002

Duda DG

Endothelial cell-based therapy for hematopoiesis

Blood. 2007;109(6):2272-3

Jain RK, Duda DG, Sorensen AG

Emerging paradigms and potential biomarkers of response and resistance in anatiangiogenic therapy of cancer

ASCO 2009 Educational Book. 2009;:716-21

Duda DG

Targeting Tumor Angiogenesis: Biomarkers of Angiogenesis and Antiangiogenic Therapy in Cancer

Angiogenesis Foundation CME e-publication. 2011;:ePub

Han HS, Martin JD, Lee J, Harris DK, Fukumura D, Jain RK, Bawendi M

Spatial Charge Configuration Regulates Nanoparticle Transport and Binding Behavior In Vivo.

Angew Chem Int Ed Engl. 2013;52(5):1414-9 - PMID: 23255143 - PMCID: PMC3755124 - DOI: 10.1002/anie.201208331

Jain RK, Munn LL, Fukumura D

Lung window preparation in mice.

Cold Spring Harb Protoc. 2013;2013(1):ePub - PMID: 23282642 - DOI: 10.1101/pdb.prot072678

Zhu AX, Ancukiewicz M, Supko JG, Sahani DV, Blaszkowsky LS, Meyerhardt JA, Abrams TA, Jackson McCleary N, Bhargava P, Muzikansky A, Sheehan S, Regan E, Vasudev E, Knowles M, Fuchs CS, Ryan DP, Jain RK, Duda DG

Efficacy, safety, pharmacokinetics and biomarkers of cediranib monotherapy in advanced hepatocellular carcinoma: A phase II study.

Clin Cancer Res. 2013;19(6):1557-66 - PMID: 23362324 - PMCID: PMC3609423 - DOI: 10.1158/1078-0432.CCR-12-3041

Chen O, Zhao J, Chauhan VP, Cui J, Wong C, Harris DK, Wei H, Han HS, Fukumura D, Jain RK, Bawendi MG

Compact high-quality CdSe-CdS core-shell nanocrystals with narrow emission linewidths and suppressed blinking.

Nat Mater. 2013;12(5):445-51 - PMID: 23377294 - PMCID: PMC3677691 - DOI: 10.1038/nmat3539

Kozin SV, Niemierko A, Huang P, Silva J, Doppke KP, Suit HD

Inter- and intramouse heterogeneity of radiation response for a growing paired organ.

Radiat Res. 2008;170(2):264-7 - PMID: 18666813 - DOI: 10.1667/RR1262.1

Huang P, Olive PL, Durand RE

Use of the comet assay for assessment of drug resistance and its modulation in vivo.

Br J Cancer. 1998;77(3):412-6 - PMID: 9472636 - PMCID: PMC2151301 - DOI: 10.1038/bjc.1998.65

Huang P, Suit HD

Spontaneous osteosarcoma in a severe combined immunodeficient (SCID/Sed) mouse.

Contemp Top Lab Anim Sci. 1996;35(6):75-7 - PMID: 16450991

Huang P, Taghian A, Hsu DW, Perez LA, Allam A, Duffy M, DaCosta A, Suit HD

Spontaneous metastasis, proliferation characteristics and radiation sensitivity of fractionated irradiation recurrent and unirradiated human xenografts.

Radiother Oncol. 1996;41(1):73-81 - PMID: 8961371 - DOI: 10.1016/s0167-8140(96)91803-4

Huang P, Taghian A, Allam A, Freeman J, Duffy M, Suit H

The effect of whole-body irradiation of nude mice on the tumor transplantability and control probability of a human soft tissue sarcoma xenograft.

Radiat Res. 1996;145(3):337-42 - PMID: 8927702

Huang P, Allam A, Taghian A, Freeman J, Duffy M, Suit HD

Growth and metastatic behavior of five human glioblastomas compared with nine other histological types of human tumor xenografts in SCID mice.

J Neurosurg. 1995;83(2):308-15 - PMID: 7616277 - DOI: 10.3171/jns.1995.83.2.0308

Allam A, Perez LA, Huang P, Taghian A, Azinovic I, Freeman J, Duffy M, Efird J, Suit HD

The effect of the overall treatment time of fractionated irradiation on the tumor control probability of a human soft tissue sarcoma xenograft in nude mice.

Int J Radiat Oncol Biol Phys. 1995;32(1):105-11 - PMID: 7721606 - DOI: 10.1016/0360-3016(95)00511-V

Huang P, Allam A, Perez LA, Taghian A, Freeman J, Suit HD

The effect of combining recombinant human tumor necrosis factor-alpha with local radiation on tumor control probability of a human glioblastoma multiforme xenograft in nude mice.

Int J Radiat Oncol Biol Phys. 1995;32(1):93-8 - PMID: 7721643 - DOI: 10.1016/0360-3016(94)00492-4

Huang P, Allam A, Taghian A, Ruka W, Freeman J, Duffy M, Suit HD

Quantitative comparison of xenotransplantation of a human soft tissue sarcoma into the subcutaneous tissue of normal, postincision, and postincision plus indomethacin-treated nude mice.

J Surg Oncol. 1995;58(4):257-62 - PMID: 7723370 - DOI: 10.1002/jso.2930580412

Huang P

[Adult nasopharyngeal mucosa xenograft and dinitrosopiperazine carcinogenesis in nude mice].

Zhonghua Yi Xue Za Zhi. 1991;71(8):441-3, 32 - PMID: 1660764

Guan EN, Zhou TC, Wang JH, Chen Y, Sun YX, Huang PG, Tang WP, Zhao ML

Effects of monoclonal antibody anti-EGF receptor on human nasopharyngeal carcinoma cell and other tumor cells.

Sci China B. 1990;33(11):1334-40 - PMID: 2095159

Guan E, Zhou TC, Wang JH, Huang PG, Tang WP, Zhao ML, Chen Y, Sun YX

Growth inhibition of human nasopharyngeal carcinoma in athymic mice by anti-epidermal growth factor receptor monoclonal antibodies.

Int J Cell Cloning. 1989;7(4):242-56 - PMID: 2768842 - DOI: 10.1002/stem.5530070406

Huang P

[Xenograft of human nasopharyngeal mucosa in nude mice].

Zhonghua Er Bi Yan Hou Ke Za Zhi. 1991;24(4):219-20, 255 - PMID: 2486076

Tang WP, Huang PG, Zhao ML, Liao SL, Zeng Y

Wikstroemia indica promotes development of nasopharyngeal carcinoma in rats initiated by dinitrosopiperazine.

J Cancer Res Clin Oncol. 1988;114(4):429-31 - PMID: 3410882 - DOI: 10.1007/BF02128191

Prabhakar U, Blakey DC, Maeda H, Jain RK, Sevick-Muraca EM, Zamboni W, Farokhzad OC, Barry ST, Gabizon A, Grodzinski P

Challenges and key considerations of the enhanced permeability and retention effect (EPR) for nanomedicine drug delivery in oncology.

Cancer Res. 2013;73(8):2412-2417 - PMID: 23423979 - PMCID: PMC3916009 - DOI: 10.1158/0008-5472.CAN-12-4561

Huang Y, Goel S, Duda DG, Fukumura D, Jain RK

Vascular normalization as an emerging strategy to enhance cancer immunotherapy.

Cancer Res. 2013;73(10):2943-8 - PMID: 23440426 - PMCID: PMC3655127 - DOI: 10.1158/0008-5472.CAN-12-4354

Snuderl M, Batista A, Kirkpatrick ND, Ruiz de Almodovar C, Riedemann L, Walsh EC, Anolik R, Huang Y, Martin JD, Kamoun W, Knevels E, Schmidt T, Farrar CT, Vakoc BJ, Mohan N, Chung E, Roberge S, Peterson T, Bais C, Zhelyazkova BH, Yip S, Hasselblatt M, Rossig C, Niemeyer E, Ferrara N, Klagsbrun M, Duda DG, Fukumura D, Xu L, Carmeliet P, Jain RK

Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma.

Cell. 2013;152(5):1065-76 - PMID: 23452854 - PMCID: PMC3587980 - DOI: 10.1016/j.cell.2013.01.036

Jain RK, Munn LL, Fukumura D

Measuring angiogenesis and hemodynamics in mice.

Cold Spring Harb Protoc. 2013;2013(4):354-8 - PMID: 23547161 - DOI: 10.1101/pdb.prot073916

Jain RK, Munn LL, Fukumura D

Measuring vascular permeability in mice.

Cold Spring Harb Protoc. 2013;2013(5):444-6 - PMID: 23637370 - DOI: 10.1101/pdb.prot074344

Stylianopoulos T, Martin JD, Snuderl M, Mpekris F, Jain SR, Jain RK

Co-evolution of solid stress and interstitial fluid pressure in tumors during progression: Implications for vascular collapse.

Cancer Res. 2013;73(13):3833-3841 - PMID: 23633490 - PMCID: PMC3702668 - DOI: 10.1158/0008-5472.CAN-12-4521

Duda DG, Munn LL, Jain RK

Can We Identify Predictive Biomarkers for Antiangiogenic Therapy of Cancer Using Mathematical Modeling?

J Natl Cancer Inst. 2013;105(11):762-5 - PMID: 23670727 - PMCID: PMC3672078 - DOI: 10.1093/jnci/djt114

Jain RK

Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers.

J Clin Oncol. 2013;31(17):2205-18 - PMID: 23669226 - PMCID: PMC3731977 - DOI: 10.1200/JCO.2012.46.3653

Jain RK, Munn LL, Fukumura D

Measuring leukocyte-endothelial interactions in mice.

Cold Spring Harb Protoc. 2013;2013(6):561-3 - PMID: 23734020 - DOI: 10.1101/pdb.prot075085

Thunemann M, Wen L, Hillenbrand M, Vachaviolos IA, Feil S, Ott T, Han X, Fukumura D, Jain RK, Russwurm M, de Wit C, Feil R

Transgenic Mice for cGMP Imaging.

Circ Res. 2013;113(4):365-71 - PMID: 23801067 - PMCID: PMC3896241 - DOI: 10.1161/CIRCRESAHA.113.301063

Jain RK, Munn LL, Fukumura D

Measuring interstitial diffusion, convection, and binding parameters in mouse tumors.

Cold Spring Harb Protoc. 2013;2013(7):678-80 - PMID: 23818670 - DOI: 10.1101/pdb.prot075721

Jain RK, Munn LL, Fukumura D

Measuring Interstitial pH and pO2 in Mouse Tumors.

Cold Spring Harb Protoc. 2013;2013(7):675-7 - PMID: 23818669 - DOI: 10.1101/pdb.prot075713

Sahani DV, Jiang T, Hayano K, Duda DG, Catalano OA, Ancukiewicz M, Jain RK, Zhu AX

Magnetic resonance imaging biomarkers in hepatocellular carcinoma: association with response and circulating biomarkers after sunitinib therapy.

J Hematol Oncol. 2013;6(1):51 - PMID: 23842041 - PMCID: PMC3722053 - DOI: 10.1186/1756-8722-6-51

Lu-Emerson C, Snuderl M, Kirkpatrick ND, Goveia J, Davidson C, Huang Y, Riedemann L, Taylor J, Ivy P, Duda DG, Ancukiewicz M, Plotkin SR, Chi AS, Gerstner ER, Eichler AF, Dietrich J, Stemmer-Rachamimov AO, Batchelor TT, Jain RK

Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma.

Neuro Oncol. 2013;15(8):1079-87 - PMID: 23828240 - PMCID: PMC3714160 - DOI: 10.1093/neuonc/not082

Pierson RN, Price DC, Wang J, Jain RK

Extracellular water measurements: organ tracer kinetics of bromide and sucrose in rats and man.

Am J Physiol. 1978;235(3):F254-64 - PMID: 696835 - DOI: 10.1152/ajprenal.1978.235.3.F254

Yamada S, Melder RJ, Leunig M, Ohkubo C, Jain RK

Leukocyte rolling increases with age.

Blood. 1995;86(12):4707-8 - PMID: 8541569

Baxter LT, Zhu H, Mackensen DG, Butler WF, Jain RK

Biodistribution of monoclonal antibodies: scale-up from mouse to human using a physiologically based pharmacokinetic model.

Cancer Res. 1995;55(20):4611-22 - PMID: 7553638

Yamada S, Mayadas TN, Yuan F, Wagner DD, Hynes RO, Melder RJ, Jain RK

Rolling in P-selectin-deficient mice is reduced but not eliminated in the dorsal skin.

Blood. 1995;86(9):3487-92 - PMID: 7579454

Baxter LT, Jain RK

Pharmacokinetic analysis of the microscopic distribution of enzyme-conjugated antibodies and prodrugs: comparison with experimental data.

Br J Cancer. 1996;73(4):447-56 - PMID: 8595158 - PMCID: PMC2074453 - DOI: 10.1038/bjc.1996.80

Swartz MA, Berk DA, Jain RK

Transport in lymphatic capillaries. I. Macroscopic measurements using residence time distribution theory.

Am J Physiol. 1996;270(1 Pt 2):H324-9 - PMID: 8769768 - DOI: 10.1152/ajpheart.1996.270.1.H324

Berk DA, Swartz MA, Leu AJ, Jain RK

Transport in lymphatic capillaries. II. Microscopic velocity measurement with fluorescence photobleaching.

Am J Physiol. 1996;270(1 Pt 2):H330-7 - PMID: 8769769 - DOI: 10.1152/ajpheart.1996.270.1.H330

Johnson EM, Berk DA, Jain RK, Deen WM

Hindered diffusion in agarose gels: test of effective medium model.

Biophys J. 1996;70(2):1017-23 - PMID: 8789119 - PMCID: PMC1225002 - DOI: 10.1016/S0006-3495(96)79645-5

Skalak R, Zargaryan S, Jain RK, Netti PA, Hoger A

Compatibility and the genesis of residual stress by volumetric growth.

J Math Biol. 1996;34(8):889-914 - PMID: 8858855 - DOI: 10.1007/BF01834825

Kaufman EN, Jain RK

Measurement of mass transport and reaction parameters in bulk solution using photobleaching. Reaction limited binding regime.

Biophys J. 1991;60(3):596-610 - PMID: 1932550 - PMCID: PMC1260103 - DOI: 10.1016/S0006-3495(91)82089-6

Nozue M, Lee I, Hartford A, Tanda S, Suit H, Jain R

pO(2) measurement in murine tumors by Eppendorf 'Histograph'.

Int J Oncol. 1996;9(5):955-62 - PMID: 21541601 - DOI: 10.3892/ijo.9.5.955

Ramanujan S, Koenig GC, Padera TP, Stoll BR, Jain RK

Local imbalance of proangiogenic and antiangiogenic factors: a potential mechanism of focal necrosis and dormancy in tumors.

Cancer Res. 2000;60(5):1442-8 - PMID: 10728711

Nugent LJ, Jain RK

Plasma pharmacokinetics and interstitial diffusion of macromolecules in a capillary bed.

Am J Physiol. 1984;246(1 Pt 2):H129-37 - PMID: 6198927 - DOI: 10.1152/ajpheart.1984.246.1.H129