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Somers RC, Lanning RM, Snee PT, Greytak AB, Jain RK, Bawendi MG, Nocera DG
A Nanocrystal-based Ratiometric pH Sensor for Natural pH Ranges.
Chem Sci. 2012;3(10):2980-2985 - PMID: 26413260 - PMCID: PMC4582792 - DOI: 10.1039/C2SC20212C
Somers RC, Lanning RM, Snee PT, Greytak AB, Jain RK, Bawendi MG and Nocera DG
A Nanocrystal-based Ratiometric pH Sensor for Natural pH Ranges.
Chemical Science. 2012;:ePub
Jain RK
Delivery of molecular and cellular medicine to solid tumors.
Adv Drug Deliv Rev. 2012;64(Suppl):353-365 - PMID: 24511174 - PMCID: PMC3914635 - DOI: 10.1016/j.addr.2012.09.011
Kirkpatrick ND, Chung E, Cook DC, Han X, Gruionu G, Liao S, Munn LL, Padera TP, Fukumura D, Jain RK
Video-rate resonant scanning multiphoton microscopy: An emerging technique for intravital imaging of the tumor microenvironment.
Intravital. 2012;1(1):ePub - PMID: 24353926 - PMCID: PMC3864876 - DOI: 10.4161/intv.21557
Kesler CT, Liao S, Munn LL, Padera TP
Lymphatic vessels in health and disease.
Wiley Interdiscip Rev Syst Biol Med. 2012;5(1):111-24 - PMID: 23209022 - PMCID: PMC3527689 - DOI: 10.1002/wsbm.1201
Jain RK, Munn LL, Fukumura D
Pancreatic tumor preparation in mice.
Cold Spring Harb Protoc. 2012;2012(12):ePub - PMID: 23209145 - DOI: 10.1101/pdb.prot072363
Jain RK, Munn LL, Fukumura D
Liver tumor preparation in mice.
Cold Spring Harb Protoc. 2012;2012(12):ePub - PMID: 23209146 - DOI: 10.1101/pdb.prot072371
Jain RK, Munn LL, Fukumura D
Lymphangiography of the mouse tail.
Cold Spring Harb Protoc. 2012;2012(11):1177-8 - PMID: 23118364 - DOI: 10.1101/pdb.prot072108
Jain RK, Munn LL, Fukumura D
Lymphangiography of the mouse ear.
Cold Spring Harb Protoc. 2012;2012(11):1179-80 - PMID: 23118365 - DOI: 10.1101/pdb.prot072116
Song JW, Daubriac J, Tse JM, Bazou D, Munn LL
RhoA mediates flow-induced endothelial sprouting in a 3-D tissue analogue of angiogenesis.
Lab Chip. 2012;12(23):5000-6 - PMID: 23073300 - PMCID: PMC3490212 - DOI: 10.1039/c2lc40389g
Kodack DP, Chung E, Yamashita H, Incio J, Duyverman AM, Song Y, Farrar CT, Huang Y, Ager E, Kamoun W, Goel S, Snuderl M, Lussiez A, Hiddingh L, Mahmood S, Tannous BA, Eichler AF, Fukumura D, Engelman JA, Jain RK
Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases.
Proc Natl Acad Sci U S A. 2012;109(45):E3119-27 - PMID: 23071298 - PMCID: PMC3494882 - DOI: 10.1073/pnas.1216078109
Huang Y, Yuan J, Righi E, Kamoun WS, Ancukiewicz M, Nezivar J, Santosuosso M, Martin JD, Martin MR, Vianello F, Leblanc P, Munn LL, Huang P, Duda DG, Fukumura D, Jain RK, Poznansky MC
Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy.
Proc Natl Acad Sci U S A. 2012;109(43):17561-6 - PMID: 23045683 - PMCID: PMC3491458 - DOI: 10.1073/pnas.1215397109
Jain RK, Munn LL, Fukumura D
Mammary fat pad chamber preparation in mice.
Cold Spring Harb Protoc. 2012;2012(10):1113-4 - PMID: 23028075 - DOI: 10.1101/pdb.prot071506
Jain RK, Munn LL, Fukumura D
Mammary fat pad tumor preparation in mice.
Cold Spring Harb Protoc. 2012;2012(10):1115-6 - PMID: 23028076 - DOI: 10.1101/pdb.prot071514
Liu J, Liao S, Diop-Frimpong B, Chen W, Goel S, Naxerova K, Ancukiewicz M, Boucher Y, Jain RK, Xu L
TGF-? blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma.
Proc Natl Acad Sci U S A. 2012;109(41):16618-23 - PMID: 22996328 - PMCID: PMC3478596 - DOI: 10.1073/pnas.1117610109
Jain RK
Delivery of molecular and cellular medicine to solid tumors.
Adv Drug Deliv Rev. 2012;:ePub - PMID: 22983334
Duda DG, Willett CG
Going beyond systemic fluoropyrimidines with radiation therapy for rectal cancer: what should be the priority?
Oncology (Williston Park). 2012;26(8):741-3 - PMID: 22957407 - PMCID: PMC3682651
Jain RK, Munn LL, Fukumura D
Corneal pocket assay in rabbits.
Cold Spring Harb Protoc. 2012;2012(9):1017-8 - PMID: 22949714 - DOI: 10.1101/pdb.prot070052
Stylianopoulos T, Martin JD, Chauhan VP, Jain SR, Diop-Frimpong B, Bardeesy N, Smith BL, Ferrone CR, Hornicek FJ, Boucher Y, Munn LL, Jain RK
Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors.
Proc Natl Acad Sci U S A. 2012;109(38):15101-8 - PMID: 22932871 - PMCID: PMC3458380 - DOI: 10.1073/pnas.1213353109
Sorensen AG, Emblem KE, Polaskova P, Jennings D, Kim H, Ancukiewicz M, Wang M, Wen PY, Ivy P, Batchelor TT, Jain RK
Increased survival of glioblastoma patients who respond to antiangiogenic therapy with elevated blood perfusion.
Cancer Res. 2012;72(2):402-7 - PMID: 22127927 - PMCID: PMC3261301 - DOI: 10.1158/0008-5472.CAN-11-2464
Goel S, Wong AH, Jain RK
Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease.
Cold Spring Harb Perspect Med. 2012;2(3):a006486 - PMID: 22393532 - PMCID: PMC3282493 - DOI: 10.1101/cshperspect.a006486
Plotkin SR, Bredella MA, Cai W, Kassarjian A, Harris GJ, Esparza S, Merker VL, Munn LL, Muzikansky A, Askenazi M, Nguyen R, Wenzel R, Mautner VF
Quantitative assessment of whole-body tumor burden in adult patients with neurofibromatosis.
PLoS One. 2012;7(4):e35711 - PMID: 22558206 - PMCID: PMC3338705 - DOI: 10.1371/journal.pone.0035711
Song JW, Bazou D, Munn LL
Anastomosis of endothelial sprouts forms new vessels in a tissue analogue of angiogenesis.
Integr Biol (Camb). 2012;4(8):857-62 - PMID: 22673771 - PMCID: PMC3759296 - DOI: 10.1039/c2ib20061a
Jain RK, Carmeliet P
SnapShot: Tumor angiogenesis.
Cell. 2012;149(6):1408-1408.e1 - PMID: 22682256 - DOI: 10.1016/j.cell.2012.05.025
Meyerhardt JA, Ancukiewicz M, Abrams TA, Schrag D, Enzinger PC, Chan JA, Kulke MH, Wolpin BM, Goldstein M, Blaszkowsky L, Zhu AX, Elliott M, Regan E, Jain RK, Duda DG
Phase I study of cetuximab, irinotecan, and vandetanib (ZD6474) as therapy for patients with previously treated metastastic colorectal cancer.
PLoS One. 2012;7(6):e38231 - PMID: 22701615 - PMCID: PMC3373492 - DOI: 10.1371/journal.pone.0038231
Dima SO, Tanase C, Albulescu R, Herlea V, Chivu-Economescu M, Purnichescu-Purtan R, Dumitrascu T, Duda DG, Popescu I
An Exploratory Study of Inflammatory Cytokines as Prognostic Biomarkers in Patients With Ductal Pancreatic Adenocarcinoma.
Pancreas. 2012;41(7):1001-7 - PMID: 22722257 - DOI: 10.1097/MPA.0b013e3182546e13
Jain RK, Munn LL, Fukumura D
Rabbit ear chambers.
Cold Spring Harb Protoc. 2012;2012(7):813-14 - PMID: 22753607 - DOI: 10.1101/pdb.prot070045
Wong HK, Shimizu A, Kirkpatrick ND, Garkavtsev I, Chan AW, di Tomaso E, Klagsbrun M, Jain RK
Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism.
Neoplasia. 2012;14(2):84-94 - PMID: 22431917 - PMCID: PMC3306254 - DOI: 10.1593/neo.111600
Chauhan VP, Stylianopoulos T, Boucher Y, Jain RK
Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies.
Annu Rev Chem Biomol Eng. 2012;2:281-98 - PMID: 22432620 - DOI: 10.1146/annurev-chembioeng-061010-114300
Tse JM, Cheng G, Tyrrell JA, Wilcox-Adelman SA, Boucher Y, Jain RK, Munn LL
Mechanical compression drives cancer cells toward invasive phenotype.
Proc Natl Acad Sci U S A. 2012;109(3):911-6 - PMID: 22203958 - PMCID: PMC3271885 - DOI: 10.1073/pnas.1118910109
Saylor PJ, Kozak KR, Smith MR, Ancukiewicz MA, Efstathiou JA, Zietman AL, Jain RK, Duda DG
Changes in biomarkers of inflammation and angiogenesis during androgen deprivation therapy for prostate cancer.
Oncologist. 2012;17(2):212-9 - PMID: 22302227 - PMCID: PMC3286170 - DOI: 10.1634/theoncologist.2011-0321
Raut CP, Boucher Y, Duda DG, Morgan JA, Quek R, Ancukiewicz M, Lahdenranta J, Eder JP, Demetri GD, Jain RK
Effects of sorafenib on intra-tumoral interstitial fluid pressure and circulating biomarkers in patients with refractory sarcomas (NCI protocol 6948).
PLoS One. 2012;7(2):e26331 - PMID: 22347360 - PMCID: PMC3274514 - DOI: 10.1371/journal.pone.0026331
Duyverman AM, Kohno M, Roberge S, Fukumura D, Duda DG, Jain RK
An isolated tumor perfusion model in mice.
Nat Protoc. 2012;7(4):749-55 - PMID: 22441293 - PMCID: PMC3375334 - DOI: 10.1038/nprot.2012.030
Duyverman AM, Steller EJ, Fukumura D, Jain RK, Duda DG
Studying primary tumor-associated fibroblast involvement in cancer metastasis in mice.
Nat Protoc. 2012;7(4):756-62 - PMID: 22441294 - PMCID: PMC3380105 - DOI: 10.1038/nprot.2012.031
Duyverman AM, Kohno M, Duda DG, Jain RK, Fukumura D
A transient parabiosis skin transplantation model in mice.
Nat Protoc. 2012;7(4):763-70 - PMID: 22441295 - PMCID: PMC3375333 - DOI: 10.1038/nprot.2012.032
Stylianopoulos T, Wong C, Bawendi MG, Jain RK, Fukumura D
Multistage nanoparticles for improved delivery into tumor tissue.
Methods Enzymol. 2012;508:109-30 - PMID: 22449923 - PMCID: PMC3774840 - DOI: 10.1016/B978-0-12-391860-4.00006-9
Vakoc BJ, Fukumura D, Jain RK, Bouma BE
Cancer imaging by optical coherence tomography: preclinical progress and clinical potential.
Nat Rev Cancer. 2012;12(5):363-8 - PMID: 22475930 - PMCID: PMC3560400 - DOI: 10.1038/nrc3235
Chauhan VP, Stylianopoulos T, Martin JD, Popovi? Z, Chen O, Kamoun WS, Bawendi MG, Fukumura D, Jain RK
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner.
Nat Nanotechnol. 2012;7(6):383-8 - PMID: 22484912 - PMCID: PMC3370066 - DOI: 10.1038/nnano.2012.45
Goel S, Fukumura D, Jain RK
Normalization of the tumor vasculature through oncogenic inhibition: An emerging paradigm in tumor biology.
Proc Natl Acad Sci U S A. 2012;109(20):E1214 - PMID: 22550180 - PMCID: PMC3356659 - DOI: 10.1073/pnas.1203794109
Kozin SV, Duda DG, Munn LL, Jain RK
Neovascularization After Irradiation: What is the Source of Newly Formed Vessels in Recurring Tumors?
J Natl Cancer Inst. 2012;104(12):899-905 - PMID: 22572994 - PMCID: PMC3379722 - DOI: 10.1093/jnci/djs239
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